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Higher Cholesterol increases the risk of
Biochemical Failure after Radical
Prostatectomy
Newswise — Poor cholesterol management may
not only affect a man’s risk for prostate
cancer, but also his risk of biomedical
recurrence after prostatectomy, according to
new data from Duke University.
Researchers,
presenting at the 103rd Annual Scientific
Meeting of the American Urological
Association (AUA), identified 471 patients
from the Shared Equal Access Regional Cancer
Hospital (SEARCH) database who underwent
radical prostatectomy between 1998 and 2007
and found that those with a high level of
low-density lipoprotein (LDL) cholesterol
and those with increased serum cholesterol
were up to 2.5 times more likely to
experience a biochemical relapse.
Researchers employed Cox proportional hazard
analysis to examine the relationships
between cholesterol, LDL and high-density
lipoprotein (HDL) levels with biomedical
recurrence independent of factors such as
age, race, statin drug use and body mass
index.
This
study, along with other research that has
linked obesity to prostate cancer, magnifies
the importance of diet and exercise in
achieving sound urologic health.
As
many urologic conditions can be linked to
cardiovascular problems, high cholesterol is
a major concern and should be monitored.
In
addition to the author, J. Brantley
Thrasher, M.D., will be on hand to answer
questions and provide third-party
perspective on the study.
About the American Urological Association
Founded in 1902 and headquartered near
Baltimore, Maryland, the American Urological
Association is the pre-eminent professional
organization for urologists, with more than
15,000 members throughout the world.
An
educational nonprofit organization, the AUA
pursues its mission of fostering the highest
standards of urologic care by carrying out a
wide variety of programs for members and
their patients, including UrologyHealth.org,
an award-winning on-line patient education
resource, and the American Urological
Association Foundation, Inc.
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