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Losing
weight after Diabetes Diagnosis can prevent
Diabetes-Related Disease
Newswise — People who lose weight soon after
a diagnosis of type 2 diabetes have better
control of their blood pressure and blood
sugar, and are more likely to maintain that
control even if they regain their weight,
according to a Kaiser Permanente study
published online in Diabetes Care, the
American Diabetes Association journal.
This is the first clinical study to show
that benefits remain even if patients regain
their weight. The study followed more than
2,500 adults with type 2 diabetes for four
years.
Those who lost weight within an average of
18 months after diagnosis were up to twice
as likely to achieve their blood pressure
and blood sugar targets as those who didn’t
lose weight. Those benefits can prevent
diabetes-related heart disease, blindness,
nerve and kidney damage, and death.
“Our study shows that early weight loss can
reduce the risk factors that so often lead
to diabetes complications and death,” says
Dr. Adrianne Feldstein, MD, MS, the study’s
lead author, a practicing physician and an
investigator at Kaiser Permanente’s Center
for Health Research in Portland, Ore.
“We’ve known for a long time that weight
loss is an important component in diabetes
treatment and prevention. Now it appears
there may be a critical window of
opportunity following diagnosis in which
some lasting gains can be achieved if people
are willing to take immediate steps toward
lifestyle changes.”
More than 20 million Americans have type 2
diabetes and most of them are overweight or
obese.
Funded by the National Institutes of Health,
the four-year study conducted by Kaiser
Permanente in Oregon and Washington followed
2,574 patients with type 2 diabetes between
1997 and 2002.
Scientists followed the weight gain and loss
patterns of these patients for three years,
and then in the fourth year compared glucose
control tests and blood pressure readings.
Most patients remained at about the same
weight during the first three years of the
study, but a small group of 314 patients
lost an average of 23 pounds.
This group was more likely to meet blood
pressure and glucose targets during the
fourth year even though, by that time, most
of them had regained their weight.
“We don’t know if the initial weight loss
increased the body’s sensitivity to insulin,
or if the sustained lifestyle changes were
the reason for the long-term health
benefits,” said Gregory A. Nichols, Ph.D., a
study co-author at Kaiser Permanente’s
Center for Health Research.
“But we do know that losing weight reduces
the risk factors that often lead to heart
disease, blindness, nerve and kidney damage,
amputations, and death in type 2 diabetes
patients.”
Although the study didn’t examine specific
methods for weight loss, prior studies
conducted at Kaiser Permanente’s Center for
Health Research have demonstrated effective
weight loss strategies.
One recent study reported that diabetic
patients who had nutritional counseling were
about twice as likely to lose weight.
Another study found that people who keep
food diaries lose twice as much weight as
those who don’t, and that people who attend
support groups also lose more weight.
This study -- The Weight Change in Diabetes
and Glycemic and Blood Pressure Control
study -- was supported by a grant from
National Institute of Diabetes and Digestive
and Kidney Diseases at the National
Institutes of Health. Study authors include:
Adrianne C. Feldstein, MD, MS; Gregory A.
Nichols, Ph.D.; David H. Smith, RPh, MHA,
Ph.D.; Victor J. Stevens, Ph.D.; A. Gabriela
Rosales, M.S. and Nancy Perrin, Ph.D. of the
Kaiser Permanente Center for Health
Research, and Keith Bachman, MD, of the
Northwest Permanente Medical Group.
Weight Loss Tips for People with
Pre-Diabetes or Diabetes
Choose whole grains, brown rice and
vegetables instead of french fries,
• white bread and white rice
• Avoid the hidden calories in processed
foods: Eat fresh foods without hidden fats
or added sweeteners whenever possible
Skip soda and fruit juice: opt instead for
sugar-free soda, tomato
• juice or water, or eat a piece of fruit
Don’t drink your calories: Except
• for 1% or non-fat milk, get your calories
from foods
Establish consistent
• eating times, including breakfast
Write down everything you eat so you
• avoid mindless eating and control how much
you eat, at home and away: a recent Kaiser
Permanente study showed that people who keep
food diaries lose twice as much weight as
those who don’t.
Educate yourself: find a registered
• dietitian or nutrition class -- a recent
Kaiser Permanente study showed that diabetic
patients who had nutritional counseling were
about twice as likely to lose weight
Visit kp.org/diabetes and kp.org/weight for
more information on
• pre-diabetes, diabetes and weight
management, in English and Spanish
Source: Kaiser Permanente
http://www.kp.org
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